This application is intended to be used as a companion tool for the manuscript entitled:
'Long-term comparative efficacy and safety of nivolumab plus ipilimumab relative to other first-line therapies for advanced non-small-cell lung cancer: a systematic literature review and network meta-analysis'   ( Link ). See below for intructions.

1. Select an outcome (OS or PFS) from the dropdown on the left panel and click 'Load data'.
2. After the data loads, click on the checkboxes for the models you'd like to compare and then click 'Compare models'.
3. The following information will then available per tab:
• Data sources - Trial data sources per population with URL links.
• HR tabular comparison - HR tables over time for each treatment vs chemo (left) and NIVO + IPI vs each treatment (right) for the chosen models.
• HR plot comparison - Plots over time for: HRs of each treatment vs chemo, HRs of NIVO + IPI vs each treatment, and hazard rates for each treatment for the chosen models.
• Survival (%) and comparison - Survival (%) tables over time for each treatment (left) and NIVO + IPI vs each treatment (right) for the chosen models.
• KM plot comparison - KM plots comparing raw (published) vs modelled data for the chosen models. Plots are separated by trial and population.
• Remaining tabs - Show the same style of plots as in 'KM plot comparison' with a separate tab for each model (not only selected models).

Note: please refer to the bottom left panel for the model nomenclature guide

Platform developed by Broadstreet HEOR